The Global Community for Colon Cancer

 

Treatment Side Effects

Because cancer treatments often damage healthy cells and tissues, side effects are common. Side effects depend mainly on the type and extent of the treatment. Side effects may not be the same for each person, and they may change from one treatment session to the next. Before treatment starts, your health care team will explain possible side effects and suggest ways to help you manage them.

Side Effect: Nausea and vomiting
Causes: Most treatments
Management:
  • There are numerous prescription medications available.
  • Treat early and aggressively.
Notes: If a medication is not working, talk to your doctor about trying something else.

Side Effect: Diarrhea  
Causes: Increased number of stools and/or change in consistency
Management:
  • Chemotherapy containing fluorouracil (5FU, Capecitabine)
  • Irinotecan
  • Prescriptions including sandostatin a long acting injection.
  • Over the counter loperamide.
Notes: After colon resection, it will take some time for your digestive system to adjust.  By trial and error you will discover which foods you can tolerate.

Side Effect: Fatigue
Causes: All treatments
  • Rest when you are tired.  
  • Plan activities when you have the most energy.
  • Ask people for help.
Fatigue may also be a result of
  • depression
  • pain
  • sleep problems
Management: Let your doctor know if you have any of these symptoms.

Side Effect: Peripheral neuropathy - Inability to tolerate cold, tingling and/or pain.
Causes: Oxaliplatin - Given with IV administration of Calcium and Magnesium for prevention of neuropathy.
Management:
  • Some anti-epileptics, anti-depressants and creams are helpful.
  • Ingest foods and liquids at room temperature.
  • Have gloves by the refrigerator.
  • Symptoms usually regress after treatment.
  • Up to 3.5% of people still have neuropathy four years after treatment ends.
  • Most frequent treatment limiting side effect.
Side Effect: Mucositis (Thrush, white patches, coldsores) - Opportunistic fungal infection can occur from the mouth to the anus.  
Causes: Chemotherapy containing fluorouracil (5FU, Capecitabine)
Management:
  • Magic™ mouthwash Anti-fungal prescription medicines.
  • Local anesthetics, analgesics.
  • Do not use hydrocortisone as it will exacerbate the mucositis.
  • Do not assume that pain is a hemorrhoid. It could be thrush, and hemorrhoid cream will worsen the condition.
  • Transient lactose intolerance may occur with mucositis.
  • Occurs in 20-50% of people on 5FU.
Side Effect: Hand and Foot Syndrome - Blistering, peeling. Affects skin and nails.
Causes: Capecitabine but may occur with 5FU
Management:
  • Mild skin creams gently applied to area.
  • ake cool showers.
  • Wear thick cotton socks, and avoid constrictive shoes.
  • Avoid friction and heat.
This information was compiled with the generous help of Colon Cancer Alliance.
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